Table 1 Overview of clinical and rat studies modeled to quantify nerve responses in VNS for stroke sequelae, inflammation, and heart failure

Human

(Dawson et al. 2021): chronically implanted helical cuff (MicroTransponder) ASCENT v1.1.1

(Fig. 7A)

(Sivaji et al. 2019):

chronically implanted ReStore cuff

ASCENT v1.1.2

(Fig. 7D)

(Koopman et al. 2016): chronically implanted helical cuff (LivaNova)

ASCENT v1.1.1

(Fig. 7B)

(Genovese et al. 2020):

chronically implanted SetPoint Medical cuff

ASCENT v1.1.2

(Fig. 7E)

(Premchand et al. 2014): chronically implanted helical cuff (LivaNova)

ASCENT v1.1.1

(Fig. 7C)

Rat

(Porter et al. 2012):

chronically implanted custom bipolar cuff

ASCENT v1.1.1

(Fig. 7G)

(Kin et al. 2021):

chronically implanted custom bipolar cuff

ASCENT v1.1.1

(Fig. 7H)

(Li et al. 2019):

chronically implanted custom bipolar cuff

ASCENT v1.1.1

(Fig. 7I)