Fig. 2

Increased Focality in rodents. A Experimental mouse set up – Position of the recording electrodes in the mouse brain [AP: −2.7, ML: + 2.04, DV: 3.2]. Plots of raw recording from electrode n°16 (highlighted in red) for standard TI with two frequencies and mTI with 8 frequencies. B Spatial distribution of Modulation Index – Shallow (electrode 26—blue) and deep contacts (electrode 7—yellow) are highlighted to facilitate localization in the modulation index plots. The maximal modulation index for both TI and mTI configuration is reached in the hippocampus (approximately electrode 16 – red). However, the focality is improved in the mTI configuration. When comparing these results with those from the previous and subsequent figures, we conclude that mTI scales well between larger and smaller anatomical geometries. Example AM modulation data from mouse 3 is shown. 5 mice were tested