Fig. 5
From: Using neural biomarkers to personalize dosing of vagus nerve stimulation
Relationship of \(\Delta\)HR to \(\Delta\)BR dependent on electrode location. Effect on HR and BR for six different stimulation locations (three electrode pairs, two polarities for each) pulse width was 500\(\,\upmu\)s with train durations of 3Â s and 5Â s, current is in mA and frequency in Hz. The train duration had no statistical effect on the relationship and is therefore not specifically labelled in the graphs. The overall location effect is significant (ANOVA, \(F(5, 39)=3.6\), \(p < 9.2\textrm{e}{-3}\)). There is a significant difference in the slopes of C4-C7-cathodic compared to other contacts (ANOVA, \(F(1, 43)=12.8\), \(p < 8.9\textrm{e}{-4}\))