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Table 3 Endoscopic Changes Post-taVNS Therapy: Retrospective Review

From: Transcutaneous auricular vagus nerve stimulation attenuates inflammatory bowel disease in children: a proof-of-concept clinical trial

Study Subject

Diagnosis

Disease location

Pre-study Endoscopic disease severity

Medication at study entry

Duration of taVNS (weeks)

Follow up endoscopic disease severity

Clinical outcome

6

CD

Right colon

SES-CD = 4

None

69

SES-CD = 3

Continued taVNS started UST

7

CD

Left colon

SES-CD = 6

Mesalamine

60

SES-CD = 2

Continued taVNS

8

CD

Left colon

SES-CD = 10

VDZ

16

SES-CD = 4

Continued taVNS

9

UC

Pancolonic

Mayo score 2

Mesalamine

21

Mayo score 2

Discontinued taVNS started VDZ

  1. SES-CD Simple Endoscopic Severity of Crohn’s disease
  2. UST Ustekinumab
  3. VDZ Vedolizumab